Recognizing Ehrlichiosis

To Ensure Prompt Treatment

Ehrlichiosis is transmitted primarily by the lone star tick, found in the southeastern and southcentral U.S.

Ehrlichiosis Mimics Other Illnesses

Ehrlichiosis is a tick-borne infection caused by bacteria called Ehrlichia (including E. chaffeensis, E. ewingii, or E. muris eauclairensis), which infect white blood cells. Ehrlichia is spread primarily by the lone star tick, found in the southeastern and south-central U.S. Ehrlichiosis symptoms usually begin within one to two weeks after a tick bite and can range from mild to severe, if not treated promptly. Because ehrlichiosis symptoms often overlap with other common illnesses, it can be easily overlooked.

Ehrlichiosis Symptoms

The most common ehrlichiosis symptoms include fever, headache, and malaise.

Ehrlichiosis Symptoms

The most common ehrlichiosis symptoms include fever, headache, and malaise.

Early Symptoms (Days 1–5):

  • Fever, chills, headache, muscle aches

  • Gastrointestinal symptoms (nausea, vomiting, diarrhea, loss of appetite)

  • Confusion

  • Rash

The rash is more common in children (up to 60%) compared to adults (<30%). It usually appears about 5 days after symptom onset and may be present on the palms and soles of feet. The rash can be splotchy red patches or pinpoint dots.

Later or Severe Symptoms (if treatment is delayed):

  • Neurological damage (for example, meningoencephalitis)

  • Respiratory failure

  • Uncontrolled bleeding

  • Organ failure, which may lead to death

Ehrlichiosis is on the rise in the US

60%
PEOPLE
Nearly 60% of people with ehrlichiosis require hospitalization.
60%
CHILDREN
A rash can occur in up to 60% of children with ehrlichiosis.
30%
ADULTS
A rash can occur in under 30% of adults with ehrlichiosis.

Ehrlichiosis: Diagnosis and Treatment

Ehrlichia, the bacterium that causes ehrlichiosis, is transmitted through tick bites and infects white blood cells. While most cases can be treated successfully, diagnosing early is imperative, since the infection can progress rapidly and cause serious complications. In fact, nearly 60% of people with ehrlichiosis are hospitalized. And, it’s estimated that 1% of cases are fatal.

Because ehrlichiosis symptoms often mimic other illnesses, diagnosis can sometimes be challenging. Therefore, healthcare providers rely on a combination of medical history, recent tick exposure, and laboratory testing to diagnose the infection.

Ehrlichiosis is treated with antibiotics. Since the illness can become serious if left untreated, doctors usually begin treatment as soon as ehrlichiosis is suspected, without waiting for test results.

Ehrlichiosis vs. Anaplasmosis: Understanding the Differences

Ehrlichiosis and anaplasmosis are both infections transmitted by tick bites that can cause similar symptoms, such as fever, headache, and fatigue. However, they are caused by different bacteria, transmitted by different types of ticks, and can affect the body in distinct ways.

Understanding the similarities and differences between these infections can help you recognize symptoms early and seek prompt treatment.

Note:The information presented on this page has been reviewed and approved by a member of our Medical Leadership Board.

Anaplasmosis symptoms typically appear 1 – 2 weeks after a tick bite and include:

Evidence of autoimmune process

Fever

Presence of infection

Chills

Determines course of treatment

Severe Headache

Presence of infection

Muscle aches

Determines course of treatment

Joint pain

Presence of infection

Fatigue

Determines course of treatment

Gastrointestinal symptoms

Presence of infection

Neurologic problems

Determines course of treatment

Rash (Uncommon)

Note: The information presented on this page has been reviewed and approved by a member of our Medical Leadership Board.

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